Microsoft: Delete an User's Profile from Windows PC

Go to Advanced settings of System as shown below, click on Settings (user profiles), select the user profile which is not loading properly in Windows, then press Delete button. Delete button will be enabled only if you login with different user account.

This will remove the entire user profile and related user SID from computer including the registery keys we talked about earlier. You can cross check the proper removal of user account (SID) by checking the C:\Users folder. Once it is remove properly, restart the computer and login with same user name (which was not loading earlier). The computer should create a new user profile as this is the first time the user is logging on. You need to copy back your old important data to new profile and set email outlook etc..if required.


Reference:
How to Fix Temporary Profile in Windows 7
http://www.sysprobs.com/fix-temporary-profile-windows-7